Rosa Rademakers Selected Research

Frontotemporal Dementia With Motor Neuron Disease

11/2019	Clinicopathologic correlations in a family with a TBK1 mutation presenting as primary progressive aphasia and primary lateral sclerosis.
3/2012	Characterization of frontotemporal dementia and/or amyotrophic lateral sclerosis associated with the GGGGCC repeat expansion in C9ORF72.

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Rosa Rademakers Research Topics

Disease

77	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 01/2022 - 03/2006
75	Frontotemporal Dementia (Semantic Dementia) 01/2022 - 05/2004
37	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 12/2021 - 09/2007
23	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 01/2008
23	Alzheimer Disease (Alzheimer's Disease) 12/2021 - 07/2008
21	Dementia (Dementias) 11/2020 - 02/2006
11	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 11/2020 - 03/2012
11	Parkinsonian Disorders (Parkinsonism) 08/2016 - 08/2006
9	Sarcoma (Soft Tissue Sarcoma) 09/2013 - 11/2009
8	Motor Neuron Disease (Primary Lateral Sclerosis) 01/2021 - 01/2008
7	Corticobasal Degeneration 11/2020 - 03/2010
7	Tauopathies 11/2020 - 05/2004
6	Proteostasis Deficiencies 01/2022 - 01/2008
6	Parkinson Disease (Parkinson's Disease) 01/2020 - 04/2008
6	Primary Progressive Aphasia 01/2019 - 09/2013
5	Atrophy 01/2021 - 03/2012
4	TDP-43 Proteinopathies 11/2017 - 09/2008
3	Pick Disease of the Brain (Pick's Disease) 01/2021 - 05/2004
3	Gliosis 10/2020 - 01/2019
3	Hereditary Diffuse Leukoencephalopathy with Spheroids 02/2019 - 12/2011
3	Cognitive Dysfunction 12/2017 - 10/2015
2	Synucleinopathies 01/2020 - 11/2015
2	Frontotemporal Dementia With Motor Neuron Disease 11/2019 - 03/2012
2	Autoimmune Diseases (Autoimmune Disease) 12/2016 - 09/2013
2	Hippocampal Sclerosis 11/2016 - 12/2011
2	Tremor (Tremors) 01/2016 - 04/2008
2	Inflammation (Inflammations) 09/2013 - 08/2006
2	Pathologic Processes 09/2011 - 08/2006
1	Disease Susceptibility (Diathesis) 01/2021
1	Anomia (Dysnomia) 01/2021
1	Demyelinating Diseases (Demyelinating Disease) 01/2020
1	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 01/2020
1	Leukoencephalopathies 02/2019
1	limbic-predominant age-related TDP-43 encephalopathy 01/2019
1	Neuroinflammatory Diseases 10/2018
1	Brain Diseases (Brain Disorder) 01/2018
1	Neuronal Ceroid-Lipofuscinoses (Neuronal Ceroid Lipofuscinosis) 09/2017

Drug/Important Bio-Agent (IBA)

64	ProgranulinsIBA 01/2021 - 08/2006
46	Proteins (Proteins, Gene)FDA Link 01/2022 - 03/2006
35	DNA-Binding Proteins (DNA Binding Protein)IBA 12/2021 - 10/2007
20	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2022 - 05/2004
19	UbiquitinIBA 10/2020 - 07/2005
11	RNA (Ribonucleic Acid)IBA 01/2022 - 08/2011
11	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 09/2007
9	Biomarkers (Surrogate Marker)IBA 01/2020 - 01/2007
8	Amyloid (Amyloid Fibrils)IBA 01/2022 - 03/2014
8	Apolipoproteins E (ApoE)IBA 01/2021 - 02/2006
7	DipeptidesIBA 10/2019 - 01/2017
6	SynucleinsIBA 01/2022 - 03/2006
5	RNA-Binding Protein FUSIBA 01/2012 - 11/2009
4	Biological ProductsIBA 01/2020 - 07/2012
4	Phosphotransferases (Kinase)IBA 11/2019 - 04/2008
4	ApolipoproteinsIBA 10/2018 - 02/2006
4	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 12/2012 - 08/2006
4	MicroRNAs (MicroRNA)IBA 10/2011 - 12/2008
3	Amino Acids FDA Link 01/2022 - 03/2013
3	GranulinsIBA 01/2022 - 11/2017
3	Heat-Shock Proteins (Heat-Shock Protein)IBA 02/2020 - 01/2018
3	NucleotidesIBA 01/2019 - 07/2015
3	Leucine (L-Leucine)FDA Link 01/2017 - 04/2008
3	Presenilin-1IBA 01/2016 - 05/2004
3	Macrophage Colony-Stimulating FactorIBA 02/2015 - 12/2011
3	Messenger RNA (mRNA)IBA 09/2013 - 07/2008
3	RNA-Binding Proteins (RNA-Binding Protein)IBA 03/2013 - 09/2011
2	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 10/2013
2	Pharmaceutical PreparationsIBA 01/2018 - 06/2014
2	N 30IBA 01/2018 - 03/2012
2	Complement System Proteins (Complement)IBA 05/2016 - 07/2010
2	poly(glycyl-alanyl)IBA 01/2016 - 10/2015
2	tau Proteins (tau Protein)IBA 01/2016 - 08/2015
2	Ataxin-2IBA 10/2014 - 08/2011
2	Nuclear Proteins (Protein, Nuclear)IBA 09/2013 - 06/2008
2	Protons (Proton)IBA 07/2013 - 08/2012
2	Glycine (Aminoacetic Acid)FDA LinkGeneric 03/2013 - 02/2012
2	sortilinIBA 12/2012 - 11/2011
2	Carrier Proteins (Binding Protein)IBA 10/2012 - 11/2007
2	Levodopa (L Dopa)FDA LinkGeneric 09/2012 - 04/2008
1	Mitochondrial DNA (mtDNA)IBA 01/2021
1	Adenosine Monophosphate (AMP)IBA 01/2021
1	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 01/2021
1	7- (6- fluoropyridin- 3- yl)- 5H- pyrido(4,3- b)indoleIBA 11/2020
1	lysosomal proteinsIBA 10/2020
1	CuprizoneIBA 01/2020
1	ethyl 4-azidophenyl-1,4-dithiobutyrimidateIBA 01/2020
1	Glucosylceramidase (Glucocerebrosidase)IBA 01/2020
1	Colony-Stimulating Factor Receptors (Colony-Stimulating Factor Receptor)IBA 02/2019
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 02/2019
1	Green Fluorescent ProteinsIBA 01/2019
1	HLA-DQA2 antigenIBA 01/2019
1	Untranslated RNA (Noncoding RNA)IBA 10/2018
1	HLA-DRB1 Chains (HLA DRB1)IBA 10/2018
1	Transcription Factors (Transcription Factor)IBA 01/2018
1	PolymersIBA 01/2018
1	Protein Isoforms (Isoforms)IBA 01/2018
1	T-Cell Intracellular Antigen-1IBA 12/2017
1	Monoclonal AntibodiesIBA 11/2017
1	Peptides (Polypeptides)IBA 11/2017
1	ElementsIBA 01/2017
1	RNA Polymerase II (RNA Polymerase B)IBA 01/2017

Therapy/Procedure

9	Therapeutics 12/2021 - 11/2011